HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 3-Acetamidopyrrolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1-Benzyl-3-acetamidopyrrolidine | HCID 4198339 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-Acetamidopyrrolidine | HCID 522715 | 89% |
Reaction Steps
A mixture of 12.5 g (0.057 mol) of the compound obtained in stage c) above, 1.3 g of 10% Pd/C, 80 ml of 95% ethanol and a drop of concentrated hydrochloric acid is hydrogenated at 40° C. When the theoretical quantity of hydrogen has been consumed, it is filtered and the filtrate is concentrated to obtain 6.5 g of the title compound in the form of an oily product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05565474 |
| Source dataset | uspto-grants-1996_10 |
| ORD ID | ord-38fe6fcfa7ee49cdbff4a80520d19ae6 |
| Source note | uspto-grants-1996_10 |