2-Bromo-7-nitro-3,4-dihydronaphthalen-1(2H)-one → 2-(4-Imidazolylmethyl)-8-nitro-4,5-dihydronaphtho[1,2-d]thiazole

HRID 865100Notes

Reaction equation

HRID 865100 reaction equation
Br[CH:2]1[CH2:11][CH2:10][C:9]2[C:4](=[CH:5][C:6]([N+:12]([O-:14])=[O:13])=[CH:7][CH:8]=2)[C:3]1=O.Cl.[NH:17]1[CH:21]=[C:20]([CH2:22][C:23]([NH2:25])=[S:24])[N:19]=[CH:18]1>>[NH:17]1[CH:21]=[C:20]([CH2:22][C:23]2[S:24][C:2]3[CH2:11][CH2:10][C:9]4[C:4](=[CH:5][C:6]([N+:12]([O-:14])=[O:13])=[CH:7][CH:8]=4)[C:3]=3[N:25]=2)[N:19]=[CH:18]1

Participants

3

Reactant 2

HCID 131941302-Bromo-7-nitro-3,4-dihydronaphthalen-1(2H)-oneHCID 178479561HCID 178479561, compound

Product 1

HCID 1785264332-(4-Imidazolylmethyl)-8-nitro-4,5-dihydronaphtho[1,2-d]thiazole

Procedure

Starting compounds: 2-bromo-7-nitro-1-tetralone, 4-imidazolylthioacetamide hydrochloride

Sources & evidence

ORD record
ord-d670a896d2104c41aa20c97ec8416f96
Source dataset
uspto-grants-1996_10
Patent number
US05565479

Reaction notes

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