Methyl iodide → 3-(3-(2-Ethoxyethoxy)-1,2,5-thiadiazol-4-yl)-1-methylpyridinium iodide

HRID 865176Notes

Reaction equation

HRID 865176 reaction equation
[CH3:1][I:2].[CH2:3]([O:5][CH2:6][CH2:7][O:8][C:9]1[C:13]([C:14]2[CH:15]=[N:16][CH:17]=[CH:18][CH:19]=2)=[N:12][S:11][N:10]=1)[CH3:4]>CC(C)=O>[I-:2].[CH2:3]([O:5][CH2:6][CH2:7][O:8][C:9]1[C:13]([C:14]2[CH:15]=[N+:16]([CH3:1])[CH:17]=[CH:18][CH:19]=2)=[N:12][S:11][N:10]=1)[CH3:4]

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 190753733-(3-(2-Ethoxyethoxy)-1,2,5-thiadiazol-4-yl)pyridine

Product 1

HCID 190753663-(3-(2-Ethoxyethoxy)-1,2,5-thiadiazol-4-yl)-1-methylpyridinium iodide

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of methyl iodide (0.5 ml, 9 mmol) and 3-(3-(2-ethoxyethoxy)-1,2,5-thiadiazol-4-yl)pyridine (4 mmol) in acetone (3 ml) was stirred at room temperature for 18 h. The title compound precipitated from the solution and was collected by filtration to yield 1.45 g (92%).

Workup

  1. customThe title compound precipitated from the solution
  2. filtrationwas collected by filtration
  3. customto yield 1.45 g (92%)

Sources & evidence

ORD record
ord-9f9362729db94ca4a668cf5e65de9b8b
Source dataset
uspto-grants-1996_10
Patent number
US05565475

Reaction notes

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