Methyl iodide → 3-(3-(4-Methylpiperidino)-1,2,5-thiadiazol-4-yl)-1-methylpyridinium iodide

HRID 865184Notes

Reaction equation

HRID 865184 reaction equation
[CH3:1][I:2].[CH3:3][CH:4]1[CH2:9][CH2:8][N:7]([C:10]2[C:14]([C:15]3[CH:16]=[N:17][CH:18]=[CH:19][CH:20]=3)=[N:13][S:12][N:11]=2)[CH2:6][CH2:5]1>CC(C)=O>[I-:2].[CH3:3][CH:4]1[CH2:5][CH2:6][N:7]([C:10]2[C:14]([C:15]3[CH:16]=[N+:17]([CH3:1])[CH:18]=[CH:19][CH:20]=3)=[N:13][S:12][N:11]=2)[CH2:8][CH2:9]1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 190753173-(3-(4-Methylpiperidino)-1,2,5-thiadiazol-4-yl)pyridine

Product 1

HCID 190753753-(3-(4-Methylpiperidino)-1,2,5-thiadiazol-4-yl)-1-methylpyridinium iodide

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of methyl iodide (0.5 ml, 8 mmol) and 3-(3-(4-methylpiperidino)-1,2,5-thiadiazol-4-yl)pyridine (0.8 g, 3.1 mmol) in acetone (5 ml) was stirred at room temperature for 18 h. The title compound precipitated from the solution and was collected by filtration to yield 1.14 g (92%).

Workup

  1. customThe title compound precipitated from the solution
  2. filtrationwas collected by filtration
  3. customto yield 1.14 g (92%)

Sources & evidence

ORD record
ord-91429a20137d490780030ee122deabbe
Source dataset
uspto-grants-1996_10
Patent number
US05565475

Reaction notes

Loading…