Methyl iodide → HCID 54462344, compound

HRID 865232Notes

Reaction equation

[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][N:9]1[C:13]([CH2:14][C@@H:15]([C:24]([OH:26])=[O:25])[NH:16][CH2:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[CH:12][N:11]=[C:10]1[CH2:27][CH2:28][CH2:29][CH3:30].[CH3:31]I>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][N:9]1[C:13]([CH2:14][C@@H:15]([C:24]([OH:26])=[O:25])[N:16]([CH2:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH3:31])=[CH:12][N:11]=[C:10]1[CH2:27][CH2:28][CH2:29][CH3:30]

Participants

Reactant 2

HCID 6328Methyl iodide

HCID 54567190HCID 54567190, compound

Product 1

HCID 54462344HCID 54462344, compound

Procedure

3-[(2-chlorophenyl)methyl]-2-n-butyl-N-benzylhistidine (prepared in Example 13) is reacted with methyl iodide to give the title compound.

Sources & evidence

ORD record: ord-9515107940724aed9d9e18278d1d1ac7
Source dataset: uspto-grants-1996_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05565480

Reaction notes

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