4-Chlorophenyl Isocyanate → HCID 19417852, compound

Participants

Reaction Steps

This benzenesulfonamide (0.99 g, 4.3 mmoles) was dissolved in acetone (4.3 ml) to which was then added 1.0N sodium hydroxide (4.4 ml). To this mixture was added 4-chlorophenylisocyanate (0.68 g, 4.4 mmoles), dissolved in 4.3 ml of acetone. This mixture was allowed to stir at room temperature for about 15 minutes. A solid was then removed from the reaction mixture by filtration. To the filtrate was added 1.0N hydrochloric acid (4.4 ml), causing separation of a brown oil. Water (5 ml) was then added and the mixture stirred until the oil had converted to a solid. The solid was collected and washed three times with water.

Provenance & Evidence