Azido(trimethyl)stannane → HCID 178438841, compound

Participants

Reaction Steps

A stirred solution of 600 mg (1.15 mmol) of the product of Example 151, Step F and 284 mg (1.38 mmol) of trimethyltin azide in 2 mL of toluene was heated with an oil bath at reflux overnight. The reaction was evaporated in vacuo, purified by silica gel flash chromatography eluting with methylene chloride/methanol/acetic acid 100:3:1, and the purified fractions concentrated in vacuo to afford 244 mg (38%) of the title compound as an amorphous solid.

Provenance & Evidence