HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nimetazepam → Nordiazepam
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nimetazepam | HCID 4496 | — |
| Reactant | Nitrazepam | HCID 4506 | — |
| Reactant | 1,3-dihydro-5-(4-methoxyphenyl)-2H-1,4-benzodiazepin-2-one | HCID 15162777 | — |
| Reactant | 1,3-dihydro-3-(4-hydroxyphenyl)-5-phenyl-2H-1,4-benzodiazepin-2-one | HCID 19078731 | — |
| Reactant | 1,3-dihydro-5-(4-methoxyphenyl)-3-(4-hydroxyphenyl)-2H-1,4-benzodiazepin-2-one | HCID 19078739 | — |
| Reactant | 1,3-dihydro-5-(2-thienyl)-2H-1,4-benzodiazepin-2-one | HCID 19078745 | — |
| Reactant | 7-chloro-1,3-dihydro-3-(4-hydroxyphenyl)-5-phenyl-2H-1,4-benzodiazepin-2-one | HCID 19078775 | — |
| Reactant | 1,3-dihydro-1-isopropyl-6-methyl-2H-1,4-benzodiazepin-2-one | HCID 19078788 | — |
| Reactant | 5-cyclohexyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one | HCID 135476124 | — |
| Product | Nordiazepam | HCID 2997 | — |
Reaction Steps
1,3-dihydro-5-(4-methoxyphenyl)-2H-1,4-benzodiazepin-2-one; 1,3-dihydro-7-nitro-5-phenyl-2H-1,4-benzodiazepin-2-one; 1,3-dihydro-1-isopropyl-6-methyl-2H-1,4-benzodiazepin-2-one; 7-nitro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one; 5-cyclohexyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 1,3-dihydro-5-(2-thienyl)-2H-1,4-benzodiazepin-2-one; 1,3-dihydro-3-(4-hydroxyphenyl)-5-phenyl-2H-1,4-benzodiazepin-2-one; 7-chloro-1,3-dihydro-3-(4-hydroxyphenyl)-5-phenyl-2H-1,4-benzodiazepin-2-one; 1,3-dihydro-5-(4-methoxyphenyl)-3-(4-hydroxyphenyl)-2H-1,4-benzodiazepin-2-one;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05567391 |
| Source dataset | uspto-grants-1996_10 |
| ORD ID | ord-65ebe607ab504fa395b915dda369c43d |
| Source note | uspto-grants-1996_10 |