反应详情

温度

50 °C

49.4 g of 2-hydrazino-6-trifluoromethoxybenzothiazole are added over one hour to 97.9 g of thionyl chloride heated to 50° C. The mixture is then heated for one hour at this same temperature and then cooled to 0° C. After addition of 200 g of an ice/water mixture (1/1 by weight), the precipitate is filtered off and washed with twice 50 cm3 of water. 54.5 g of 2-chloro-6-trifluoromethoxybenzothiazole are thus obtained, melting at 50° C.

1. temperatureThe mixture is then heated for one hour at this same temperature
2. temperaturecooled to 0° C
3. filtrationthe precipitate is filtered off
4. washwashed with twice 50 cm3 of water