HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 21469960, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | N-Hydroxysuccinimide | HCID 80170 | — |
| Reactant | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Reactant | HCID 10731954 | HCID 10731954 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 21469960 | HCID 21469960 | 79.5% |
Reaction Steps
To a susupension of N-hydroxysuccinimide (0.56 g) and 6-heptyloxy-2-naphthoic acid (1.39 g) in methylene chloride (42 ml) was added 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride (1.21 g) and stirred for 3 hours at room temparature. The reaction mixture was added to water (100 ml). The organic layer was separated and dried over magnesium sulfate. Magnesium sulfate was filtered off, and the filtrate was evaporated under reduced pressure to give succinimido 6-heptyloxy-2-naphthoate (1.48 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05569646 |
| Source dataset | uspto-grants-1996_10 |
| ORD ID | ord-06d4049e86f14959b56981d4bfc36264 |
| Source note | uspto-grants-1996_10 |