Sodium Perchlorate → HCID 19974075, compound

HRID 865951Notes

Reaction equation

HRID 865951 reaction equation
[Br-].[CH2:2]([N+:9]1[C:13]([CH3:14])=[CH:12][S:11][C:10]=1[CH:15]1OCCO1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[Cl:20]([O-:24])(=[O:23])(=[O:22])=[O:21].[Na+]>O>[Cl:20]([O-:24])(=[O:23])(=[O:22])=[O:21].[CH3:14][C:13]1[N+:9]2=[CH:2][C:3]3[CH:4]=[CH:5][CH:6]=[CH:7][C:8]=3[CH:15]=[C:10]2[S:11][CH:12]=1

Participants

4

Reactant 2

HCID 522606Sodium PerchlorateHCID 19974089HCID 19974089, compound

Product 1

HCID 19974075HCID 19974075, compoundYield 64%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To 25 g of polyphosphoric acid heated at 110° C. was added with stirring 3-benzyl-2-(1,3-dioxolan-2-yl)-4-methylthiazolium bromide (2.31 7 g, 7.9 mmol) and the mixture was stirred for 3 h. The mixture was cooled to room temperature, poured into 200 ml of water, and treated with 3 g of sodium perchlorate. The precipitated product was filtered, washed with water, ether and dried in vacuo to afford 1.5 g (64%) of 3-methylthiazolo[3,2-b]isoquinolinium perchlorate (Formula II: A=3-methylthiazolo;R1 =R6 =H; X- =ClO4-).

Workup

  1. filtrationThe precipitated product was filtered
  2. washwashed with water, ether
  3. customdried in vacuo

Sources & evidence

ORD record
ord-09e9a9c5b78d422e99061abb598bc7c3
Source dataset
uspto-grants-1996_10
Patent number
US05569655

Reaction notes

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