反应详情

温度

8 °C

Ammonia (20 l/h) is passed at 20° C. into a solution of 1,106 g (7 mol) of dimethyl cyclopropanedicarboxylate in 700 ml of methanol, with stirring. After approximately 10 hours, addition of NH3 is stopped, and the reaction mixture is cooled to 8° C. The solid formed is filtered off with suction, then washed using 200 g of cold methanol. After drying the product, 926.2 g (92.5%) of methyl 1-aminocarbonylcyclopropanecarboxylate are obtained (m.p.: 157° C.).

1. customThe solid formed
2. filtrationis filtered off with suction
3. washwashed
4. dry with materialAfter drying the product, 926.2 g (92.5%) of methyl 1-aminocarbonylcyclopropanecarboxylate
5. customare obtained (m.p.: 157° C.)