HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Nitrobenzimidazole → ethyl 2-(5-nitro-1H-benzimidazol-1-yl)octanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Nitrobenzimidazole | HCID 7195 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Ethyl 2-bromooctanoate | HCID 95580 | — |
| Product | ethyl 2-(5-nitro-1H-benzimidazol-1-yl)octanoate | HCID 21468840 | 22.9% |
Reaction Steps
5-Nitrobenzimidazole (0.109 moles, 17.8 g.) was reacted with sodium hydride (0.122 moles, 4.9 g of 60% in mineral oil) and ethyl 2-bromooctanoate (0.102 moles, 22 ml) as in Example 11 to produce a mixture of the 5 and 6 isomer. The isomers were separated to yield 7.8 g of ethyl 2-(5-nitro-1H-benzimidazol-1-yl)octanoate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05569768 |
| Source dataset | uspto-grants-1996_10 |
| ORD ID | ord-12d825dd15164e01a421af8838766e84 |
| Source note | uspto-grants-1996_10 |