Pyrrolidine-1-carbonitrile → Methyl 1-pyrrolidinecarboximidate

HRID 866331Notes

Reaction equation

HRID 866331 reaction equation

[N:1]1([C:6]#[N:7])[CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:8][O-:9].[Na+]>CO>[N:1]1([C:6](=[NH:7])[O:9][CH3:8])[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 73737Pyrrolidine-1-carbonitrile

HCID 10942334Sodium Methoxide

Product 1

HCID 13531128Methyl 1-pyrrolidinecarboximidate

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In the manner given in Example 2, 1-pyrrolidinecarbonitrile is treated with sodium methoxide in methanol to give methyl 1-pyrrolidinecarboximidate.

Sources & evidence

ORD record: ord-cbd3a468924b4b0ea4caf01a3e16ac5d
Source dataset: uspto-grants-1978_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04098791

Reaction notes

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