4-Morpholinecarbonitrile → Methyl 4-morpholinecarboximidate

HRID 866334Notes

Reaction equation

HRID 866334 reaction equation

[N:1]1([C:7]#[N:8])[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[CH3:9][O-:10].[Na+]>CO>[N:1]1([C:7](=[NH:8])[O:10][CH3:9])[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 737384-Morpholinecarbonitrile

HCID 10942334Sodium Methoxide

Product 1

HCID 13531143Methyl 4-morpholinecarboximidate

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In the manner given in Example 2, 4-morpholinecarbonitrile is treated with sodium methoxide in methanol to give methyl 4-morpholinecarboximidate.

Sources & evidence

ORD record: ord-4d6011a122e44f6e8d42c9126ec65a43
Source dataset: uspto-grants-1978_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04098791

Reaction notes

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