Phosphorus pentachloride → HCID 86735828, compound

HRID 866358Notes

Reaction equation

HRID 866358 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:14]([OH:16])=O)[C:5]([CH2:11][O:12][CH3:13])=[CH:6][C:7]=1[N+:8]([O-:10])=[O:9].P(Cl)(Cl)(Cl)(Cl)[Cl:18]>C1C=CC=CC=1>[Cl:1][C:2]1[CH:3]=[C:4]([C:14]([Cl:18])=[O:16])[C:5]([CH2:11][O:12][CH3:13])=[CH:6][C:7]=1[N+:8]([O-:10])=[O:9]

Participants

4

Reactant 2

HCID 24819Phosphorus pentachlorideHCID 86735827HCID 86735827, compound

Product 1

HCID 86735828HCID 86735828, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

A mixture of 4-chloro-α-methoxy-5-nitro-o-toluic acid (3.6 g.) and phosphorus pentachloride (3.0 g.) in 120 ml of benzene is refluxed for thirty minutes. The mixture is then concentrated in vacuo and the residue boiled with 200 ml of hexane and filtered hot. The filtrate is partially concentrated and chilled to give 2.5 g. of white solid with mp 63°-65°.

Workup

  1. temperatureis refluxed for thirty minutes
  2. concentrationThe mixture is then concentrated in vacuo
  3. filtrationfiltered hot
  4. concentrationThe filtrate is partially concentrated
  5. temperaturechilled
  6. customto give 2.5 g

Sources & evidence

ORD record
ord-72d1d137ef194a8fa71a3a68607ab1f6
Source dataset
uspto-grants-1978_07
Patent number
US04098812

Reaction notes

Loading…