反应详情

A sample of 4-chloro-α-methoxy-5-nitro-o-toluoyl chloride (1.5 g.) is added to 100 ml of ether saturated with ammonia. During the addition and for 15 minutes thereafter, the reaction temperature is kept below 20°. The precipitated solid is collected and washed well with water. The crude product (0.9) has an infrared compatible with the desired structure.

1. additionDuring the addition
2. customis kept below 20°
3. customThe precipitated solid is collected
4. washwashed well with water