反应详情

In a solution of glacial acetic acid (2750 ml) and water (250 ml) was dissolved 150 g (0.75 mol) of 1-(4-chlorophenyl)-2-imidazolidinone with heating. The solution was cooled to room temperature, and sodium nitrite (70 g, 1.0 mol) in water (200 ml) was added dropwise over 1 hour. The mixture was stirred for another 6 hours, diluted with water (1.5 l.) and the product (137 g, 81%) was collected, m.p. 154°-156°.

1. temperaturewith heating
2. customthe product (137 g, 81%) was collected