HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 866486Generated: October 25, 2026
Water → 3-(3,5-Dichlorophenyl)-2,4-imidazolidinedione
https://huagongshe.com/reaction/866486
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Hydantoic acid | HCID 10020 | — |
| Reactant | N-[[(3,5-dichlorophenyl)amino]carbonyl]glycine | HCID 595293 | — |
| Solvent | Chlorobenzene | HCID 7964 | — |
| Product | 3-(3,5-Dichlorophenyl)-2,4-imidazolidinedione | HCID 168691 | 95.6% |
Reaction Steps
To a suspension of 3-(3,5-dichlorophenyl)-ureidoacetic acid (813 g.) in chlorobenzene (3,500 cc.) is added concentrated sulphuric acid (d = 1.83) (16 cc.), representing 0.095 mol per mol of ureidoacetic acid. The water formed in the reaction is removed by azeotropic distillation. After 45 minutes' distillation, a limpid solution is obtained. After cooling to about 15° C, the precipitate formed is filtered off and washed on the filter with ethanol (500 cc.) at 10° C. After drying, 3-(3,5-dichlorophenyl)-hydantoin (724 g.) melting at 199° C is obtained. Yield: 95.4%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04099008 |
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| Source dataset | uspto-grants-1978_07 |
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| ORD ID | ord-be996351cfeb41cdad920d3b577d1ac0 |
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| Source note | uspto-grants-1978_07 |
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