HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 866488Generated: October 25, 2026
Water → 3-(3,5-Dichlorophenyl)-2,4-imidazolidinedione
https://huagongshe.com/reaction/866488
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Benzenesulfonic Acid | HCID 7371 | — |
| Reactant | N-[[(3,5-dichlorophenyl)amino]carbonyl]glycine | HCID 595293 | — |
| Solvent | Chlorobenzene | HCID 7964 | — |
| Product | 3-(3,5-Dichlorophenyl)-2,4-imidazolidinedione | HCID 168691 | 90.6% |
Reaction Steps
To a suspension of 3-(3,5-dichlorophenyl)-ureidoacetic acid (26.3 g.) in chlorobenzene (180 cc.) is added benzenesulphonic acid (1.2 g. representing 0.068 mol per mol of ureidoacetic acid). The water formed in the reaction is removed by azeotropic distillation. After 30 minutes' distillation, a limpid solution is obtained. After cooling to about 15° C, the precipitate formed is filtered off and washed on the filter with ethanol (25 cc.) at 10° C. After drying, 3-(3,5-dichlorophenyl)-hydantoin (22.2 g.) melting at 199° C is obtained. Yield: 90.5%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04099008 |
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| Source dataset | uspto-grants-1978_07 |
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| ORD ID | ord-c2f494f9b56c4c209ba7eec1f8842a1e |
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| Source note | uspto-grants-1978_07 |
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