HCID 20319472, compound → HCID 20319478, compound

Participants

Reaction Steps

23 g (90 mmols) of the above 3,12-diethyl-3,12-dimethyl-1,2-diazacyclododecane are hydrogenated, in 200 ml of cyclohexane in a stirred autoclave and with the addition of 3 g of rhodium-aluminum oxide catalyst (5% by weight of Rh), for 17 hours at 200° C. After filtering off the catalyst and stripping off the solvent on a rotary evaporator, the residue is fractionated at 0.2 mm Hg. This gives 7.7 g (30%) of 1,10-diethyl-1,10-dimethyl-1,10-diaminodecane as a colorless oil, boiling point 118°-22° C/0.2 mm Hg, nD20 = 1.4597.

Provenance & Evidence