Propionitrile → 15049-86-2

HRID 866536Notes

Reaction equation

HRID 866536 reaction equation
[C:1](#[N:4])[CH2:2][CH3:3].[P:5]([OH:8])([OH:7])[OH:6]>C(O)C>[NH2:4][C:1]([P:5]([OH:8])([OH:7])=[O:6])([P:5]([OH:8])([OH:7])=[O:6])[CH2:2][CH3:3]

Participants

4

Reactant 2

HCID 7854PropionitrileHCID 107909Phosphorous acid

Product 1

HCID 436880715049-86-2Yield 52%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
150 °C

Procedure

A mixture of propionitrile (5.5 g, 0.1 mole), phosphorous acid (16.4 g, 0.2 mole), ISOPAR-M (22 g), and wetting agents (0.5 g each) was heated under nitrogen at ambient pressure for 2 hours at 150° C. The product was worked up with ethanol. Colorless crystals of 1-amino-1,1-diphosphono propane (52% yield), m.p. 282° C was obtained.

Sources & evidence

ORD record
ord-88da0865ed22445a9186c09c184713e6
Source dataset
uspto-grants-1978_07
Patent number
US04100167

Reaction notes

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