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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 866633Generated: October 30, 2026

Benzylamine → Alafosfalin

https://huagongshe.com/reaction/866633

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzylamineHCID 7504—
ReactantHCID 13002188HCID 13002188—
ProductAlafosfalinHCID 71957—

Reaction Steps

In a manner analogous to that described in the last paragraph of Example A, starting from the benzylamine salt of (1R)-1-[(N-benzyloxycarbonyl-L-alanyl)amino]-ethylphosphonic acid there was obtained (1R)-1-(L-alanylamino)-ethylphosphonic acid of melting point 295°-296° C (decomposition); [α]D20 = -45.6° (c = 1% in water).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04100275
Source datasetuspto-grants-1978_07
ORD IDord-919c8c4fc6f4486f8446f8950a4637d0
Source noteuspto-grants-1978_07