Formic Acid → HCID 53741131, compound

HRID 866641Notes

Reaction equation

HRID 866641 reaction equation
[OH:1][CH2:2][CH2:3][NH:4][C:5]1[C:10]([NH2:11])=[C:9]([Cl:12])[N:8]=[CH:7][N:6]=1.[CH:13](O)=[O:14]>>[OH:1][CH2:2][CH2:3][NH:4][C:5]1[C:10]([NH:11][CH:13]=[O:14])=[C:9]([Cl:12])[N:8]=[CH:7][N:6]=1

Participants

3

Reactant 2

HCID 284Formic AcidHCID 2445272-((5-Amino-6-chloro-4-pyrimidinyl)amino)ethanol

Product 1

HCID 53741131HCID 53741131, compound

Procedure

The starting 4-β-hydroxyethylamino-5-formamido-6-chloropyrimidine was prepared by heating in 80% formic acid, 4-β-hydroxyethylamino-5-amino-6-chloropyrimidine, M.P. (Koffer) 139° C, itself prepared according to the method of SCHAEFFER and BHARGAVA, Biochemistry (1965) 71.

Sources & evidence

ORD record
ord-bb0eb6aedb11463aa3b03d57ceaff51e
Source dataset
uspto-grants-1978_07
Patent number
US04100286

Reaction notes

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