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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 866687Generated: November 3, 2026

Ethyl formate → Cyclooctanone, 2-(hydroxymethylene)-

https://huagongshe.com/reaction/866687

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl formateHCID 8025—
ReactantCyclooctanoneHCID 10403—
ProductCyclooctanone, 2-(hydroxymethylene)-HCID 1382068—

Reaction Steps

As in previous examples, 126 g of cyclooctanone, XXVIc, was reacted with ethyl formate to give 95 g (0.62 mol) of 2-hydroxymethylene-cyclooctanone, XXVIIc, bp 87°-92° C (0.4 mm).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04100353
Source datasetuspto-grants-1978_07
ORD IDord-806811e168d4457cb81ead322f57c7df
Source noteuspto-grants-1978_07