1-[1,5-Di-(bicyclo[2.2.2]oct-2-yl)-3-pentyl]-5-(2,3-dihydroxypropyl)-9,9-di-(2,3-dihydroxypropyl)-1,5,9-triazanonane → 1-[1,5-Di-(bicyclo[2.2.2]oct-2-yl)-3-pentyl]-5-(2,3-dihydroxypropyl)-1,5,9-triazanonane

HRID 866714Notes

Reaction equation

HRID 866714 reaction equation
OC(CO)CN(CC(O)CO)CCCN.OC(CO)CN(CC(O)CO)CCCN(CC(O)CO)CCCN.[CH:40]12[CH2:47][CH2:46][CH:43]([CH2:44][CH2:45]1)[CH2:42][CH:41]2[CH2:48][CH2:49][CH:50]([NH:61][CH2:62][CH2:63][CH2:64][N:65]([CH2:80][CH:81]([OH:84])[CH2:82][OH:83])[CH2:66][CH2:67][CH2:68][N:69](CC(O)CO)CC(O)CO)[CH2:51][CH2:52][CH:53]1[CH2:58][CH:57]2[CH2:59][CH2:60][CH:54]1[CH2:55][CH2:56]2>>[CH:54]12[CH2:60][CH2:59][CH:57]([CH2:56][CH2:55]1)[CH2:58][CH:53]2[CH2:52][CH2:51][CH:50]([NH:61][CH2:62][CH2:63][CH2:64][N:65]([CH2:80][CH:81]([OH:84])[CH2:82][OH:83])[CH2:66][CH2:67][CH2:68][NH2:69])[CH2:49][CH2:48][CH:41]1[CH2:42][CH:43]2[CH2:46][CH2:47][CH:40]1[CH2:45][CH2:44]2

Participants

4

Reactant 3

HCID 203198351-[1,5-Di-(bicyclo[2.2.2]oct-2-yl)-3-pentyl]-5-(2,3-dihydroxypropyl)-9,9-di-(2,3-dihydroxypropyl)-1,5,9-triazanonaneHCID 234677983,3'-[(3-Aminopropyl)azanediyl]di(propane-1,2-diol)HCID 234678171,1,5-Tri-(2,3-dihydroxypropyl)-1,5,9-triazanonane

Product 1

HCID 203198391-[1,5-Di-(bicyclo[2.2.2]oct-2-yl)-3-pentyl]-5-(2,3-dihydroxypropyl)-1,5,9-triazanonane

Procedure

In a like manner and using analogous quantities, but employing N,N-di-(2,3-dihydroxypropyl)trimethylenediamine and 1,1,5-tri-(2,3-dihydroxypropyl)-1,5,9-triazanonane instead of 3,3'-(2,3-dihydroxypropylimino)bispropylamine there are prepared respectively N-[1,5-di-(bicyclo[2.2.2]oct-2-yl)-3-pentyl]-N'-di-(2,3-dihydroxypropyl)trimethylenediamine, and 1-[1,5-di-(bicyclo[2.2.2]oct-2-yl)-3-pentyl]-5-(2,3-dihydroxypropyl)-9,9-di-(2,3-dihydroxypropyl)-1,5,9-triazanonane.

Sources & evidence

ORD record
ord-6bb1b61399d44436a8f9fb503106946f
Source dataset
uspto-grants-1978_07
Patent number
US04100193

Reaction notes

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