HCID 131711154, compound → 30566-83-7

Participants

Reaction Steps

5-(N-Benzyl-N-tert.butylglycyl)-o-anisic acid, methyl ester, hydrochloride (4.05g) in ethanol (60 ml) was added to a pre-reduced suspension of 10% Pd/C (1.0g) in ethanol (15 ml) and hydrogenated until uptake ceased (hydrogen uptake was 441.cc). The catalyst was filtered off and the filtrate evaporated to dryness to afford 5-(2-tert.butylamino-1-hydroxyethyl)-o-anisic acid, methyl ester, hydrochloride as a white crystalline solid (2.9g) m.p. 189°-194° .

Provenance & Evidence