HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 20318584, compound → 5-(2-Amino-1-hydroxyethyl)-o-anisamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 20318584 | HCID 20318584 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 5-(2-Amino-1-hydroxyethyl)-o-anisamide | HCID 20318583 | — |
Reaction Steps
A solution of 5-(N,N-dibenzylglycyl)-o-anisamide (3.88g) in tetrahydrofuran (25 ml) and ethanol (125ml) was added to a pre-reduced suspension of 10% Pd/C (1.0g) in ethanol (25 ml). Uptake of hydrogen ceased within 14 hours. The catalyst was filtered off and the solvent evaporated under reduced pressure to leave 5-(2-amino-1-hydroxyethyl)-o-anisamide as a colourless gum.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04101579 |
| Source dataset | uspto-grants-1978_07 |
| ORD ID | ord-4f0d162cc99e46d8bdd5aa4995cc500b |
| Source note | uspto-grants-1978_07 |