Isopropylamine → N-Isopropyl-3,4-dimethyl-2,6-dinitroaniline

HRID 866799노트

반응식

HRID 866799 반응식
Cl[C:2]1[C:3]([N+:13]([O-:15])=[O:14])=[C:4]([CH3:12])[C:5]([CH3:11])=[CH:6][C:7]=1[N+:8]([O-:10])=[O:9].[CH:16]([NH2:19])([CH3:18])[CH3:17]>>[CH:16]([NH:19][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([CH3:11])=[C:4]([CH3:12])[C:3]=1[N+:13]([O-:15])=[O:14])([CH3:18])[CH3:17]

참가 물질

3

반응물 2

HCID 6363IsopropylamineHCID 134551024-Chloro-3,5-dinitro-o-xylene

생성물 1

HCID 12767671N-Isopropyl-3,4-dimethyl-2,6-dinitroaniline수율 80%

실험 절차

4-Chloro-3,5-dinitro-o-xylene (10.0 grams, 0.043 mole) and i-propylamine (10.1 grams, 0.17 mole) are mixed and refluxed for 12 hours using an efficient reflux condenser. The mixture is then cooled and poured into 100 ml. of 5% hydrochloric acid and extracted with diethyl ether. The ether extract is dried over magnesium sulfate. Removal of the drying agent and solvent leaves an orange oil which readily solidifies. The product is recrystallized from methanol to give 8.7 grams (80%) of an orange solid with melting point 69° C. to 70° C.

후처리

  1. temperaturerefluxed for 12 hours
  2. temperatureThe mixture is then cooled
  3. additionpoured into 100 ml
  4. extractionof 5% hydrochloric acid and extracted with diethyl ether
  5. extractionThe ether extract
  6. dry with materialis dried over magnesium sulfate
  7. customRemoval of the drying agent and solvent
  8. customleaves an orange oil which
  9. customThe product is recrystallized from methanol

출처 및 근거

ORD 기록
ord-0ee27f6f1f7c4670b82bc89a151fe229
출처 데이터셋
uspto-grants-1978_07
특허 번호
US04101582

반응 노트

불러오는 중…