Acetic Anhydride → HCID 131711160, compound

Participants

Reaction Steps

A solution of 3-hydrazonomethyl-7-(2-thienylacetamido)-3-cephem-4-carboxylic acid (93 mg) in a mixture of acetic anhydride (0.5 ml) and pyridine (0.2 ml) is kept at room temperature for 45 hours. The mixture is diluted with ether. The obtained precipitate is collected by filtration and dried to leave 3-(2-acetylhydrazono)methyl-7-(2-thienylacetamido)-3-cephem-4-carboxylic acid monohydrate (101 mg). m.p. 184°-190° C (decomposition). Yield: 96%.

Provenance & Evidence