反应详情

A solution of 13.4 g. of 2-aminopyridine in 300 ml. of pyridine is treated with 31.0 g. of 4-acetylbenzenesulfonyl chloride and the solution is stirred at room temperature for 6 hours. The solution is poured into 1 l. of cold water and the resulting precipitate of 4-acetyl-N-(2-pyridyl)benzensulfonamide is collected by filtration, washed with water and dried; m.p. 201°-202° C. after crystallization from methanol.

1. additionThe solution is poured into 1 l
2. filtrationof cold water and the resulting precipitate of 4-acetyl-N-(2-pyridyl)benzensulfonamide is collected by filtration
3. washwashed with water
4. customdried
5. customm.p. 201°-202° C. after crystallization from methanol