反应详情

The damp 4-acetylbenzenesulfonyl chloride from 100 g. of sodium 4-acetylbenzenesulfonate is added to a solution of 114 g. of 3-piperidinemethanol in 900 ml. of water. The mixture is stirred at room temperature for 16 hours, cooled, and the precipitate for 1-(4-acetylbenzenesulfonyl)-3-piperidinemethanol collected by filtration, washed with water and dried; m.p. 104°-106° C. after crystallization from aqueous ethanol.

1. temperaturecooled
2. filtrationthe precipitate for 1-(4-acetylbenzenesulfonyl)-3-piperidinemethanol collected by filtration
3. washwashed with water
4. customdried
5. customm.p. 104°-106° C. after crystallization from aqueous ethanol