HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → 5,6-Dimethoxy-2-methyl-3-indoleglyoxylyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 5,6-dimethoxy-2-methyl-1H-indole | HCID 266596 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 5,6-Dimethoxy-2-methyl-3-indoleglyoxylyl chloride | HCID 13195539 | — |
Reaction Steps
8.7 g of oxalyl chloride are added dropwise to a stirring solution, cooled to about -10° C., of 12.0 g of 5,6-dimethoxy-2-methylindole in 250 ml of ether. After addition is complete, the mixture is stirred for 10 minutes, producing a bright orange precipitate of 5,6-dimethoxy-2-methyl-3-indole glyoxylyl chloride which is immediately used for the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04101663 |
| Source dataset | uspto-grants-1978_07 |
| ORD ID | ord-a37182b788a24968963f3ce9159c97cb |
| Source note | uspto-grants-1978_07 |