Water → 2-(4-Fluorophenyl)-4-(3-methanesulfonyloxyphenyl)-5-methoxypyrimidine

HRID 86703Notes

Reaction equation

HRID 86703 reaction equation
[CH3:23][S:24]([Cl:25])(=[O:26])=[O:27].[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][cH:10][c:11]([O:21][CH3:22])[c:12](-[c:14]3[cH:15][c:16]([OH:20])[cH:17][cH:18][cH:19]3)[n:13]2)[cH:6][cH:7]1.[OH2:34].[cH:28]1[cH:29][cH:30][n:31][cH:32][cH:33]1>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][cH:10][c:11]([O:21][CH3:22])[c:12](-[c:14]3[cH:15][c:16]([O:20][S:24]([CH3:23])(=[O:26])=[O:27])[cH:17][cH:18][cH:19]3)[n:13]2)[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 962WaterHCID 1049PyridineHCID 31297Methanesulfonyl chlorideHCID 14883712HCID 14883712, compound

Product 1

HCID 148837572-(4-Fluorophenyl)-4-(3-methanesulfonyloxyphenyl)-5-methoxypyrimidine

Sources & evidence

ORD record
ord-04087591034047e3b0dfdf5c4aade4df
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…