N-bromobutanimide → HCID 54087782, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 7.0 g (0.024 mol) of 1-(4-bromophenyl)-1-(3-pyridyl)-propene and 4.6 g (0.024 mol) of N-bromosuccinimide in 600 ml of carbontetrachloride was heated with stirring to 80° C. Then 0.5 g. of α,α-azabisbutyronitrile was added as radical initiator and the mixture was refluxed for 2 hours. After cooling to ambient temperature, the reaction mixture was filtered and the filtrate was evaporated in vacuo to 100 ml. NMR on the residual solution indicated a 1:1-mixture of the E- and Z-3-(4-bromophenyl)-3-(3-pyridyl)allylbromides. This solution was used directly in the preparation of the end product without further purification.

Provenance & Evidence