7-[2-(3Oxo-5-phenyl-1-trans-pentenyl)-4-oxo-3-thiazolidinyl]heptanoic acid → 7-[2-(3-Hydroxy-1-trans-octenyl)-4-oxo-3thiazolidinyl]heptanoic Acid

HRID 867104Notes

Reaction equation

HRID 867104 reaction equation
[O:1]=[C:2]([CH2:20][CH2:21][C:22]1C=CC=[CH:24][CH:23]=1)/[CH:3]=[CH:4]/[CH:5]1[N:9]([CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][C:16]([OH:18])=[O:17])[C:8](=[O:19])[CH2:7][S:6]1.O=C(CCCCC)/C=C/C1N(CCCCCCC(O)=O)C(=O)CS1>>[OH:1][CH:2]([CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])/[CH:3]=[CH:4]/[CH:5]1[N:9]([CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][C:16]([OH:18])=[O:17])[C:8](=[O:19])[CH2:7][S:6]1

Participants

3

Reactant 2

HCID 203173827-[2-(3Oxo-5-phenyl-1-trans-pentenyl)-4-oxo-3-thiazolidinyl]heptanoic acidHCID 203173977-[2-(3-Oxo-1-trans-octenyl)4-oxo-3-thiazolidinyl]heptanoic acid

Product 1

HCID 203174057-[2-(3-Hydroxy-1-trans-octenyl)-4-oxo-3thiazolidinyl]heptanoic Acid

Procedure

This compound is prepared essentially by the method as described in Example 13, Step D, except that the 7-[2-(3oxo-5-phenyl-1-trans-pentenyl)-4-oxo-3-thiazolidinyl]heptanoic acid is replaced with 7-[2-(3-oxo-1-trans-octenyl)4-oxo-3-thiazolidinyl]heptanoic acid. Chromatographic purification of the product resulting this method on silica gel affords the title compound as a pale yellow, viscous oil.

Workup

  1. customThis compound is prepared essentially by the method
  2. customChromatographic purification of the product
  3. customresulting this method on silica gel

Sources & evidence

ORD record
ord-304ef532b0144992b3ddd899f785d577
Source dataset
uspto-grants-1978_07
Patent number
US04102888

Reaction notes

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