7-[2-(3-Hydroxyoctyl)-4-oxo-3-thiazolidinyl]heptanoic acid → 7-[2-(3-Hydroxy-1-trans-octenyl)-1,4-dioxo3-thiazolidinyl]heptanoic Acid

HRID 867105Notes

Reaction equation

HRID 867105 reaction equation
[OH:1][CH:2]([CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])[CH2:3][CH2:4][CH:5]1[N:9]([CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][C:16]([OH:18])=[O:17])[C:8](=[O:19])[CH2:7][S:6]1.[OH:25]C(CCCCC)/C=C/C1N(CCCCCCC(O)=O)C(=O)CS1>>[OH:1][CH:2]([CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])/[CH:3]=[CH:4]/[CH:5]1[N:9]([CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][C:16]([OH:18])=[O:17])[C:8](=[O:19])[CH2:7][S:6]1=[O:25]

Participants

3

Reactant 2

HCID 203173917-[2-(3-Hydroxyoctyl)-4-oxo-3-thiazolidinyl]heptanoic acidHCID 203174057-[2-(3-Hydroxy-1-trans-octenyl)-4-oxo-3thiazolidinyl]heptanoic Acid

Product 1

HCID 203174097-[2-(3-Hydroxy-1-trans-octenyl)-1,4-dioxo3-thiazolidinyl]heptanoic Acid

Procedure

This compound is prepared essentially by the method as described in Example 2 except that the 7-[2-(3-hydroxyoctyl)-4-oxo-3-thiazolidinyl]heptanoic acid is replaced by 7-[2-(3-hydroxy-1-trans-octenyl)-4-oxo-3-thiazolidinyl]-heptanoic acid. This method affords the title compound as a viscous, essentially colorless oil after purification by column chromatography on silica gel.

Workup

  1. customThis compound is prepared essentially by the method

Sources & evidence

ORD record
ord-376c1020002a4b8ea89e4243f0bffe97
Source dataset
uspto-grants-1978_07
Patent number
US04102888

Reaction notes

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