N,N-Dimethyl-1,3-propanediamine → HCID 20317663, compound

Participants

Reaction Steps

2.5 grams of N,N-dimethyl-1,3-propane diamine was added to a cold solution of 5 grams 1-adamantane carboxylic acid chloride in 15 cc benzene. An immediate precipitate formed. The mixture was stirred and permitted to sit for thirty minutes. The precipitate was washed with benzene several times, centrifuged, and dried in vacuum, yielding 5 grams of N-(3-dimethylaminopropyl)adamantane-1- carboxamide hydrochloride having a melting point of 154°-157° C. This product was dissolved in 150 cc acetone, placed in a refrigerator for crystal growth and 4.8 gms of the product was recovered.

Provenance & Evidence