Dicyandiamide → 3'-METHYLTHIOBENZOGUANAMINE

HRID 867157Notes

Reaction equation

HRID 867157 reaction equation
[CH3:1][S:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[C:6]#[N:7].[C:11]([N:13]=[C:14]([NH2:16])[NH2:15])#[N:12].[OH-].[K+]>COCCO.O>[NH2:12][C:11]1[N:13]=[C:14]([NH2:16])[N:15]=[C:6]([C:5]2[CH:8]=[CH:9][CH:10]=[C:3]([S:2][CH3:1])[CH:4]=2)[N:7]=1

Participants

6

Reactant 3

HCID 10005DicyandiamideHCID 14797Potassium HydroxideHCID 130328133-(Methylsulfanyl)benzonitrile

Product 1

HCID 232743593'-METHYLTHIOBENZOGUANAMINE

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 80192-MethoxyethanolSolvent

Procedure

4.0 g of m-methylthiobenzonitrile, 2.7 g of dicyanodiamide and 2.0 g of caustic potash are dissolved in 20 ml of methyl cellosolve, and the mixture is refluxed for 4 hours. After cooling, the mixture is diluted with water and the separated crystals are recrystallized from dioxane. Melting point: 229°-230° C.; Yield: 3.4 g.

Workup

  1. temperaturethe mixture is refluxed for 4 hours
  2. temperatureAfter cooling
  3. customthe separated crystals are recrystallized from dioxane

Sources & evidence

ORD record
ord-f9c4f945bcff4a7a943f567d996a24c9
Source dataset
uspto-grants-1978_07
Patent number
US04103009

Reaction notes

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