4-Isopropyl-5,5-dimethyl-oxazolidin-2-one → 3-[4-[4-(3,5-Dimethyl-2-pyridinyl)piperazine-1-carbonyl]-3-methylphenyl]-5,5-dimethyl-4-propan-2-yl-1,3-oxazolidin-2-one

HRID 86723Notes

Reaction equation

HRID 86723 reaction equation
[Br:1][c:2]1[cH:3][c:4]([CH3:24])[c:5]([C:8](=[O:9])[N:10]2[CH2:11][CH2:12][N:13]([c:16]3[n:17][cH:18][c:19]([CH3:23])[cH:20][c:21]3[CH3:22])[CH2:14][CH2:15]2)[cH:6][cH:7]1.[CH:25]([CH3:26])([CH3:27])[CH:28]1[NH:29][C:30](=[O:35])[O:31][C:32]1([CH3:33])[CH3:34]>>[c:2]1([N:29]2[CH:28]([CH:25]([CH3:26])[CH3:27])[C:32]([CH3:33])([CH3:34])[O:31][C:30]2=[O:35])[cH:3][c:4]([CH3:24])[c:5]([C:8](=[O:9])[N:10]2[CH2:11][CH2:12][N:13]([c:16]3[n:17][cH:18][c:19]([CH3:23])[cH:20][c:21]3[CH3:22])[CH2:14][CH2:15]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 36126874-Isopropyl-5,5-dimethyl-oxazolidin-2-oneHCID 58484835(4-Bromo-2-methylphenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone

Product 1

HCID 673807893-[4-[4-(3,5-Dimethyl-2-pyridinyl)piperazine-1-carbonyl]-3-methylphenyl]-5,5-dimethyl-4-propan-2-yl-1,3-oxazolidin-2-one

Sources & evidence

ORD record
ord-35d9c427cdd040ffa9e9d5d7bf00cfc4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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