2-Chloro-4-iodopyridine → 2'-Chloro-6-cyclopropyl-4-(4-trifluoromethylphenyl)-[2,4']bipyridinyl

HRID 86729Notes

Reaction equation

HRID 86729 reaction equation
[CH:1]1([c:4]2[cH:5][c:6](-[c:18]3[cH:19][cH:20][c:21]([C:24]([F:25])([F:26])[F:27])[cH:22][cH:23]3)[cH:7][c:8]([O:10][S:11]([C:12]([F:13])([F:14])[F:15])(=[O:16])=[O:17])[n:9]2)[CH2:2][CH2:3]1.[Cl:28][c:29]1[n:30][cH:31][cH:32][c:33]([I:35])[cH:34]1>>[CH:1]1([c:4]2[cH:5][c:6](-[c:18]3[cH:19][cH:20][c:21]([C:24]([F:25])([F:26])[F:27])[cH:22][cH:23]3)[cH:7][c:8](-[c:33]3[cH:32][cH:31][n:30][c:29]([Cl:28])[cH:34]3)[n:9]2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 15165112-Chloro-4-iodopyridineHCID 57468747Trifluoro-methanesulfonic acid 6-cyclopropyl-4-(4-trifluoromethyl-phenyl)-pyridin-2-yl ester

Product 1

HCID 866154432'-Chloro-6-cyclopropyl-4-(4-trifluoromethylphenyl)-[2,4']bipyridinyl

Sources & evidence

ORD record
ord-5854cec2e139403093c3b18e5b2c5f97
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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