HRID867301

反应详情

EQUATION

反应方程式

HRID 867301 的结构方程式

REACTANTS

反应物

2

结构：C1CCNCC1

Piperidine

C5H11N

结构：COC(=O)[C@@H]1C[C@@H](OC(=O)N2Cc3cccc(Br)c3C2)CN1C(=O)OCc1ccccc1

未命名化合物

PRODUCTS

生成物

1

结构：COC(=O)[C@@H]1C[C@@H](OC(=O)N2Cc3cccc(N4CCCCC4)c3C2)CN1C(=O)OCc1ccccc1

未命名化合物

收率 43.36%

AUXILIARIES

试剂、催化剂与溶剂

4

结构：O=P([O-])([O-])[O-].[K+].[K+].[K+]

试剂HCID62657

Tripotassium phosphate

K3O4P

结构：[Cu][I]

催化剂HCID24350

Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)

CuI

结构：O=C(O)C(=O)Nc1c(F)cccc1F

催化剂HCID28710784

未命名化合物

结构：CS(C)=O

Dimethyl sulfoxide

C2H6OS

2 次

CONDITIONS

反应条件

温度: 80 °C

WORKUP

后处理

additionThe reaction vials were then cooled to r.t. and diluted with 100 μL of 5% AcOH in DMSO, containing 1,3,5-trimethoxybenzene (0.005M) and were shaken vigorously.
aliquot25 microliter of resulting solution is taken
additionTo the 25 microliter aliquot 700 microliter of MeCN was added prior to UPLC-MS Analysis