Thionyl Chloride → HCID 56633257, compound

Participants

Reaction Steps

10 ml of thionyl chloride was added to 2.0 g of α-dodecyloxypropionicacid, and the mixture was refluxed under heat for 2 hours. Excess of thionyl chloride was distilled off to obtain α-dodecyloxypropionic acid chloride. 20 ml of dry pyridine was added thereto, and 5.0 g of 4,4'-dihydroxybiphenyl was further added dropwise. After the addition, themixture was refluxed under heat for 3 hours, charged into ice water, and extracted with benzene. The extract was purified with a silica gel column chromatography to obtain 4-hydroxy-4'-α-dodecyloxypropanoyloxybiphenyl.

Provenance & Evidence