Ethanol → HCID 13882129, compound

HRID 867377Notes

Reaction equation

HRID 867377 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:12]([C:13]#[N:14])=[C:11]([C:15]([O:17]CC)=[O:16])[CH:10]=[N:9]2)=[CH:4][CH:3]=1.[OH-].[Na+].C([OH:24])C>O>[C:15]([C:11]1[CH:10]=[N:9][N:8]([C:5]2[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=2)[C:12]=1[C:13]([NH2:14])=[O:24])([OH:17])=[O:16]

Participants

5

Reactant 3

HCID 702EthanolHCID 14798Sodium HydroxideHCID 13772949Ethyl 1-(4-chlorophenyl)-5-cyano-1H-pyrazole-4-carboxylate

Product 1

HCID 13882129HCID 13882129, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

The process of Example 2 was followed, starting with 3.7 g. of ethyl 1-(4-chlorophenyl)-5-cyano-4-pyrazolecarboxylate and 2 g. of sodium hydroxide in 60 ml. of denatured ethanol and 60 ml. of water to obtain 2.3g. of the desired product, m.p. 249°-250°. The elemental analysis was as follows.

Sources & evidence

ORD record
ord-37e7c33b28334584a518a612763c35d4
Source dataset
uspto-grants-1988_10
Patent number
US04775409

Reaction notes

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