Dichloromethane → 1-(4-{4-[3-(4-Fluoro-phenyl)-5-hydroxymethyl-isoxazol-4-yl]-imidazol-1-yl}-phenyl)-ethanone

HRID 86739Notes

Reaction equation

HRID 86739 reaction equation
[B:30]([Br:31])([Br:32])[Br:33].[Cl:34][CH2:35][Cl:36].[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][o:10][c:11]([CH2:27][O:28][CH3:29])[c:12]2-[c:13]2[n:14][cH:15][n:16](-[c:18]3[cH:19][cH:20][c:21]([C:24]([CH3:25])=[O:26])[cH:22][cH:23]3)[cH:17]2)[cH:6][cH:7]1>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][o:10][c:11]([CH2:27][OH:28])[c:12]2-[c:13]2[n:14][cH:15][n:16](-[c:18]3[cH:19][cH:20][c:21]([C:24]([CH3:25])=[O:26])[cH:22][cH:23]3)[cH:17]2)[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 25134Boron tribromideHCID 67420992HCID 67420992, compound

Product 1

HCID 674206471-(4-{4-[3-(4-Fluoro-phenyl)-5-hydroxymethyl-isoxazol-4-yl]-imidazol-1-yl}-phenyl)-ethanone

Sources & evidence

ORD record
ord-d4f5d2da72644d45960ed479933bc3dd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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