Penicillamine → HCID 15725079, compound

Participants

Reaction Steps

1.46 g (1.39 ml, 10 mmoles) of 2-formylbenzofuran are added to a solution containing 1.5 g (10 mmoles) of D-penicillamine in 150 ml of methanol while stirring. After 48 hours, the solution is evaporated to dryness under reduced pressure. The syrupic residue is dissolved in hot benzene and filtered. After adding petroleum ether, the title compound is precipitated in a crystalline form with a yield of 1.9 g (68.6%), m.p.: 96° C., [α]D20 =+215° (c=0.511, dimethylsulphoxide).

Provenance & Evidence