Penicillamine → HCID 2825599, compound

Participants

Reaction Steps

A mixture containing 6 g (30 mmoles) of 2-carboxybenzaldehyde and 6 g (30 mmoles) of D-penicillamine in 44 ml of water is stirred for 3 hours. The precipitate is filtered out and washed with aqueous methanol to given the crude title acid in a yield of 9.86 g (82.6%) which can be recrystallized from methanol containing water, m.p.: 185°-186° C. [α]D18 =+385° (c=0.51, methanol).

Provenance & Evidence