Penicillamine → HCID 11837461, compound

Participants

Reaction Steps

3.5 g (20 mmoles) of 2,4-dichlorobenzaldehyde dissolved in 17 ml of methanol are added to a solution containing 3.0 g (20 mmoles) of D-penicillamine in 65 ml of water while stirring. After stirring for 16 hours, the precipitate is filtered, washed with 50% methanol and dried to give the title acid in a yield of 5.82 g (95%), m.p.: 150°-151° C., [α]D20 =+353° (c=0.45, dimethylsulphoxide).

Provenance & Evidence