4-Chlorobenzaldehyde → HCID 15725087, compound

Participants

Reaction Steps

4.2 g (30 mmoles) of 4-chlorobenzaldehyde are given to the suspension containing 5.73 g (30 mmoles) of N-acetyl-D-penicillamine in 18 ml of ethereal hydrogen chloride solution under stirring for 12 minutes. After dissolution, a product is precipitated which is filtered out and washed with ether to give 8.32 g (88.4%) of the title compound, m.p.: 197°-198° C. after recrystallization from ethyl acetate, [α]D =+230.5° (c=0.59, methanol).

Provenance & Evidence