Glycine ethyl ester → HCID 14281021, compound

HRID 867499Notes

Reaction equation

HRID 867499 reaction equation
[O:1]=[C:2]1[NH:21][C:5]2=[N:6][C:7]3[CH:8]=[CH:9][C:10]([O:14][CH2:15][CH2:16][CH2:17][C:18]([OH:20])=O)=[CH:11][C:12]=3[CH:13]=[C:4]2[NH:3]1.[CH2:22]([O:24][C:25](=[O:28])[CH2:26][NH2:27])[CH3:23]>>[CH2:22]([O:24][C:25](=[O:28])[CH2:26][NH:27][C:18](=[O:20])[CH2:17][CH2:16][CH2:15][O:14][C:10]1[CH:9]=[CH:8][C:7]2[N:6]=[C:5]3[NH:21][C:2](=[O:1])[NH:3][C:4]3=[CH:13][C:12]=2[CH:11]=1)[CH3:23]

Participants

3

Reactant 2

HCID 12176Glycine ethyl esterHCID 142809904-(2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]quinolin-7-yloxy)-butyric acid

Product 1

HCID 14281021HCID 14281021, compound

Procedure

This compound, m.p. 274°-276° C., was prepared analogous to Example 15 from 4-[(2,3-dihydro-2-oxo-1H-imidazo[4,5-b]quinolin-7-yl)oxy]butyric acid and glycine ethyl ester.

Sources & evidence

ORD record
ord-6cce3a8ccd2f40f2bca0e708e0cfb6a7
Source dataset
uspto-grants-1988_10
Patent number
US04775674

Reaction notes

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